The hosts are in dire need of a win after slipping out of the top four following a string of disappointing results, while the visitors enter the weekend in the relegation zone.
Match preview
Francesco Farioli was dubbed as one of the managerial appointments of the season when he had his Nice side challenging with Paris Saint-Germain at the top of Ligue 1 in the early stages of the season.
Even into the new year, Nice were still the second-best side in the division even though PSG had pulled clear, but form in 2024 has been extremely disappointing and costly.
Defensively solidity was the basis of everything behind Nice's early success, and they still have the best record in the league, having conceded just 17 goals in 24 games, but shortcomings in other areas have bore their heads in recent weeks.
Nice are now winless in five league matches, taking just two points in that spell, losing to top-four rivals Monaco and relegation-candidates Lyon and Toulouse.
In the past two weeks, Lille and Monaco have both risen above Nice, who have gone from having a comfortable buffer in second, to slipping outside the Champions League places altogether.
Now sitting fifth, Nice are only one point ahead of a rampant Lens side, who are also making impressive strides up the table.
With just eight points separating third and ninth in Ligue 1, Nice's season still could go either way, but if recent form continues, they will be lucky to compete in Europe at all next season.
Montpellier represent ideal opponents for Farioli's men to face next though, as they have won six of the last seven meetings between the clubs here at home, including a 6-1 success last season.
Nice's only win since January also came against their upcoming opponents in the last 16 of the Coupe de France a few weeks ago, as they put poor league form to one side and beat Montpellier 4-1 on the road.
It is therefore no surprise that for the visitors, that sort of form has transferred into the league for Michel Der Zakarian's men too, as Montpellier enter the fixture in the relegation playoff spot.
While Clermont are beginning to become cut adrift at the foot of the table, the relegation picture remains wide open, with the entirety of the bottom half still in trouble.
Montpellier are just one point from safety behind Le Havre, and came from behind twice to earn a respectable point against Strasbourg last time out, but wins will be required if they want to distance themselves from relegation.
With PSG up next, Montpellier could really do with a result here, as many sides at the bottom are also playing each other in the coming weeks.
Away form has been hard to come by though, as no side has fewer points on the road than La Paillade, and six of their final 10 games are away from the Stade de la Mosson, including huge clashes with Clermont and Le Havre in their next two after this trip.
Nice Ligue 1 form:
W
D
L
L
D
L
Nice form (all competitions):
D
W
L
L
D
L
Montpellier HSC Ligue 1 form:
D
L
L
W
L
D
Montpellier HSC form (all competitions):
L
L
L
W
L
D
Team News
Nice will be able to welcome Youssouf Ndayishimiye after the Burundi man was suspended for the defeat at Toulouse last week.
The hosts will remain without some important first-team players though, as Sofiane Diop, Morgan Sanson and Valentin Rosier are all out injured.
Montpellier will be without the man who scored the only goal in their crushing defeat to Nice recently, as Modibo Sagnan is suspended after picking up a third booking in just five games.
Falaye Sacko is a recent name added to the visitor's injury list as he missed last week's clash with Strasbourg, joining Axel Gueguin, Becir Omeragic and Christopher Jullien on the sidelines in what is becoming a defensive crisis for Montpellier.
Nice possible starting lineup:
Bulka; Lotomba, Todibo, Dante, Bard; Thuram, Boudaoui, Rosario; Guessand, Moffi, Boga
Montpellier HSC possible starting lineup:
Lecomte; Tchato, Sainte-Luce, Kouyate, Sylla; Ferri, Chotard, Savanier; Nordin, Adams, Al Tamari
We say: Nice 1-0 Montpellier HSC
Goals have been hard to come by all season for Nice, but even their defence has been unable to bail them out in recent weeks as their slide down the table has continued.