Having both returned to winning ways last time out, the teams will be full of confidence ahead of their meeting which promises to be an exciting watch.
Match preview
Harrogate Town recorded their largest victory of the season so far as they emphatically saw off the threat of Rochdale in a 4-1 win on December 3.
After going behind to James Ball's opener, Simon Weaver's men rallied and hit back through goals from George Thomson and Samuel Folarin either side of Luke Armstrong's brace.
Consequently, the Sulphurites occupy 20th place in the League Two table, five points clear of relegation danger despite playing one game fewer.
Awaiting them next is the challenge of an opposing outfit who have lost each of the last two meetings between the teams after emerging triumphant in the three clashes prior to that.
Off the back of a first home win since October in their most recent outing in front of their fans, Monday's hosts set out to put an another dominant display and continue their recent upturn in form.
Grimsby Town ended a six-game winless run in the league courtesy of a 2-1 victory over Tranmere Rovers at the Blundell Park two Saturdays ago.
Goals in either half from Brendan Kiernan and Niall Maher put Paul Hurst's men in the driving seat, before Jake Burton pulled one back midway through the second period.
With 27 points from their 20 matches this term, The Mariners are 14th in the standings, six points adrift of the final promotion playoff place.
However, 16 of the 27 points currently on the board for Monday's visitors have come away from home and they will be aiming to secure another positive result on the road.
Harrogate Town League Two form:
L
L
D
L
W
W
Harrogate Town form (all competitions):
W
D
L
W
L
W
Grimsby Town League Two form:
L
L
L
D
L
W
Grimsby Town form (all competitions):
L
D
L
W
L
W
Team News
Harrogate's Luke Armstrong has netted five times in his last five games and the striker will be aiming to come up trumps for his side in this one.
Twenty-three-year-old Kyle Ferguson will be expected to retain a starting spot having made his long-awaited return to action for the hosts last time out.
Fit-again Danny Amos was reinstated to the Grimsby XI against Tranmere and he should see off competition from Evan Khouri to feature at left-back once again.
Despite failing to find the back of the net since October, Harry Clifton remains the visitors' top scorer heading into Monday's contest where the Welshman will set out to end an 11-game goal drought.
Harrogate Town possible starting lineup:
Jameson; Headley, Burrell, Ferguson, Ramsay; Thomson, Falkingham; Grant, Coley, Folarin; Armstrong
Grimsby Town possible starting lineup:
Crocombe; Efete, Waterfall, Maher, Amos; Green, Holohan, Clifton; Khan, Kiernan, McAtee