The on-loan Chelsea goalkeeper was unable to feature against parent club last weekend, where Mark Travers deputised well but could do little about a late Christopher Nkunku winner.
With Kepa back in the fold - and likely back in the starting lineup - Bournemouth's only two absentees should be Tyler Adams and Dango Ouattara, recuperating from back and ankle problems respectively.
The majority of the starters from last weekend should be retained, but Evanilson may be fearing for his place up front, having missed a penalty against Chelsea as he still awaits his first Premier League goal.
The ex-Porto man is at risk of losing his spot to the fit-again Enes Unal, who could spearhead an attacking quartet also comprising Antoine Semenyo, Justin Kluivert and Marcus Tavernier at Anfield.
Lewis Cook and Ryan Christie will be expected to reprise their roles in midfield, although Philip Billing offers a physical presence and could also throw hit hat into the ring for a starting position.
As Kepa returns to the first XI, the Blues loanee should be protected by an unaltered rearguard of Milos Kerkez, Marcos Senesi, Adam Smith and Ilya Zabarnyi, who ought to be in for a rough afternoon.
Bournemouth possible starting lineup:
Kepa; Smith, Zabarnyi, Senesi, Kerkez; Christie, Cook; Semenyo, Kluivert, Tavernier; Unal