Head coach Igor Angelovski is expected to stick with a 3-5-2 formation, with Darko Velkovski, Visar Musilu and Kire Ristevski all likely to start in the back-three.
Width in the team is set be provided by left wing-back Ezgjan Alioski, who played 36 times in the Premier League for Leeds United last season, while Stefan Ristovski could feature on the opposite flank.
Napoli midfielder Eljif Elmas - who scored the winning goal against Germany in a 2-1 victory in March - could be joined in central midfield by Arijan Ademi and Boban Nikolov, although both Ferhan Hasani and Enis Bardhi will be looking to force their way into the first XI.
Aleksandar Trajkovski - who has scored four goals in his last five international matches - is set to be joined up front by experienced forward and captain Goran Pandev.
The 37-year-old talisman is North Macedonia's most capped player (119) and their all-time leading goalscorer with 37 strikes to his name.
North Macedonia possible starting lineup: Dimitrievski; Velkovski, Musliu, Ristevski; Ristovski, Nikolov, Ademi, Elmas, Alioski; Pandev, Trajkovski
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