The Reds are likely to start with an experienced side against Manchester United on Tuesday, with Mohamed Salah - fresh from signing a new contract at the club - potentially featuring in the final third of the field.
Diogo Jota and Roberto Firmino are also in line for spots in attack, meaning that new signing Darwin Nunez might have to accept a spot on the bench from the first whistle.
A familiar midfield three of Jordan Henderson, Thiago and Naby Keita might take to the field from the start, while Fabio Carvalho should make his debut following his arrival from Fulham.
There will be no Calvin Ramsay for the Merseyside giants, though, as the recent arrival from Aberdeen is yet to train with his new teammates due to an issue that was discovered during his medical.
Alex Oxlade-Chamberlain, who continues to be linked with an exit, will be among those hoping to impress during pre-season, and there is every chance that Klopp will name different XIs for each half of their opening pre-season friendly with the 20-time English champions.
Youngsters Stefan Bajcetic, Isaac Mabaya, Bobby Clark, Tom Hill, James Norris, Melkamu Frauendorf and Tyler Morton could earn minutes on Tuesday, while Harvey Elliott and Curtis Jones should also play a part against Erik ten Hag's side.
Liverpool possible starting lineup: Alisson; Alexander-Arnold, Matip, Van Dijk, Robertson; Henderson, Thiago, Keita; Jota, Firmino, Salah