Ahead of the big occasion, De Stadionclub boast some of the competition's top scorers, and on-loan Genk striker Cyriel Dessers will lead the line once again, after scoring his 10th goal of the continental campaign in the semi-final win over Marseille.
Supporting the Nigeria international in a probable 4-2-3-1 formation, which coach Arne Slot could tweak to form a 4-3-3 setup, will be Arsenal loanee Reiss Nelson and Colombian winger Luis Sinisterra - apparently a transfer target for the Gunners.
Sinisterra has already racked up six goals in the Conference League, and should cause plenty of problems for former Feyenoord wing-back Rick Karsdorp, if selected on the right flank for Roma.
Alireza Jahanbakhsh and Patrik Walemark provide other options for Slot out wide, but are more likely to appear from the bench during the second half.
Israeli goalkeeper Ofir Marciano should start behind the back four, as Justin Bijlow has been sidelined by injury since early spring.
The latter has travelled to Tirana after finally returning to training last week, and could take his place among the substitutes as part of a fully-fit squad.
Feyenoord possible starting lineup: Marciano; Geertruida, Trauner, Senesi, Malacia; Aursnes, Kokcu; Nelson, Til, Sinisterra; Dessers