Harry Kane hit four first half goals to become the top scoring England player in a singular calendar year and make it consecutive hat-tricks during the international break as Gareth Southgate's men ran riot on the road.
The Tottenham talisman also became the first England player to score four goals in just one half of action since Ian Wright did in 1993, with San Marino once again the opponents that day.
Harry Maguire gave the hosts the lead after just five minutes with his second in as many games before an own goal put the visitors in control.
England almost got their second moments later when Emile Smith Rowe's header from his Arsenal teammate Bukayo Saka's cross was blocked by a San Marino defender.
Saka thought he had his third goal in an England shirt after just a quarter of an hour's play as he twisted a turned in the box before firing a deflected effort into the corner, but it was later given as an Filippo Fabri own goal.
Foden almost got on the scoresheet with a spectacular overhead kick which just went wide of the post and after a VAR check, England were awarded a penalty as his effort struck the hand of Donte Rossi.
Kane then slotted the resulting penalty to make history by becoming the top scoring England player in a singular calendar year.
Harry Maguire gave the hosts the lead after just five minutes with his second in as many games before an own goal put the visitors in control.
Kane then struck from the spot following a mindless handball, before the striker got his second after slotting home tidily shortly after.
The Spurs striker hit his second a little over three minutes later after Emile Smith Rowe's ball into the box from the left was missed by a number of players but Kane was on hand to turn and shoot first time into the bottom corner.
He completed his hat-trick - his fifth for England and second in two games - with a second penalty in the 39th minute having himself won the penalty when his header was handled by Alessandro D'Addario.
Kane's fourth came moments later as the Tottenham forward weaved through the area and fired into the bottom corner, making it 6-0.
With his goals, the 28-year-old remarkably made it seven goals in two appearances and joined Gary Lineker in joint-third in the all-time scoring charts for England with 47 goals, but he is still behind Bobby Charlton (49) and Wayne Rooney (53) in the all-time list.
And Dean Ashton, speaking on co-commentary duty for talkSPORT, couldn't hide his admiration for the forward.
"He just loves breaking records does Harry Kane. He's a ruthless striker," the former Premier League striker noted.
Smith Rowe crowned his first England start by making it 7-0 just before the hour mark when he slotted home following a neat flick by substitute Tammy Abraham.
"What a great moment," Ashton remarked. "He's just taken that Arsenal form and brought it into the England fold."
Roma striker Tammy Abraham made it 9-0 when he controlled Trent Alexander-Arnold's cleverly lofted ball on his thigh and turned to fire home.
Saka headed England's 10th goal of the night from another Alexander-Arnold cross in what was the easiest victory in history for England.
Not since beating the USA in 1964 had England reached double figures as they kept their foot on the accelerator until the very end of this most one-sided of encounters.
Their biggest victory ever, however, remains in 1882 where they dispatched Ireland 13-0 in a friendly.