Mexico can cement their place as frontrunners in the Qatar 2022 World Cup CONCACAF qualifiers when they travel to face El Salvador at Estadio Cuscatlan in San Salvador.
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El Tri head off to take on La Selecta, three points ahead of the USMNT at the top of the table - and they know that victory will maintain the gap at the very least.
Ahead of the game, Goal has the details of how to watch on TV, stream online, team news and more.
TV channel, live stream & how to watch
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Team news & rosters
*denotes uncapped player
Almost four decades have passed since La Selecta last reared their head at a World Cup - competing at Spain 1982 - and their prospects of reaching Qatar look to be growing smaller by the day too.
But a victory over the group leaders would bolster their prospects enormously when it comes to keeping up a pursuit of a top-three spot - and that vital fourth-place playoff berth.
Predicted El Salvador starting XI: Gonzalez; Tamacas, Vigil, Dominguez, Roldan; Mena; Ceren, Henriquez; Hernandez; Monterroza, Rivas.
El Tri swept to a comfortable victory last time out - and with the USMNT's defeat, they have been able to open up a gap at the summit that will help them breathe a little easier as they set their sights on next year's tournament.
But they will be wary of a potential banana-skin in the shape of their hosts, and will look to make sure they can avoid any potential slip-ups.
Predicted Mexico starting XI: Ochoa; L. Rodriguez, Montes, Moreno, Gallardo; Herrera, Alvarez, Cordova; Corona, Jimenez, Lozano.