Steven Gerrard's side will be brimming with confidence following a 6-1 victory over Motherwell at the weekend, while things have also seen an upturn in their European exploits.
A 2-0 win over Brondby at Ibrox two weeks kick-started the Scottish champions' hopes of progressing to the next round of the competition, but with three fixtures left there's still plenty of work to do.
Gerrard will need his team on top form if they're to get a result against the Danish side.
Brondby v Rangers: Date and time
The Europa League clash is set to take place on Thursday, November 4.
It will be played at Brondby Stadium, Denmark with a UK kick-off time of 5.45pm.
Victory will put Rangers firmly on contention to qualify for the knockout stages of the competition.
Brondby v Rangers: Live commentary
Commentary will get underway at 5.30pm with coverage coming from Alex Crook and Matt Holland.
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Brondby v Rangers: Team news
Brondby will be without goalkeeper Mads Hermansen for the clash with Rangers.
The stopper will miss out with a foot injury, while defender Rasmus Wikstrom looks likely to be out until the New Year.
Elsewhere Mikael Uhre also looks set to miss out.
For Rangers, Gerrard could be without Glen Kamara for the clash in Denmark.
The midfielder received a kick to his ankle, leading Gerrard to to rate him as '50-50′ for the clash.
Meanwhile Ryan Kent has traveled with the squad and could feature.
Brondby v Rangers: What has been said?
Rangers boss Gerrard said: "We have to realise this is a different environment.
"It will be a tricky tie against a team in a must-win situation.
"I think they will be aggressive and go for it so we need to be ready for whatever comes our way.
"Europa League games away from home are always a challenge.
"Daniel Agger has told me to expect a top atmosphere so it is one we are looking forward to."
"We need to prepare to our best and are going to try and win the match.
"The aim is to have European football here after Christmas so we all have to keep driving forward."