Three days on from the Gunners' disappointing 2-0 home loss to West Ham United, head coach Mikel Arteta has made three changes to his starting XI, where the returning Kai Havertz also joins Nketiah and Kiwior in a refreshed team.
Havertz, who missed the West Ham encounter due to suspension, replaces Leandro Trossard in the Gunners' engine room, while Nketiah has been given the nod over Gabriel Jesus in the Gunners' attack.
Oleksandr Zinchenko does not make the squad at all due to a calf injury, so Kiwior is given the nod to start at left-back, in spite of Takehiro Tomiyasu's return to the matchday squad from a calf issue of his own.
Meanwhile, Fulham head coach Marco Silva has also made a trio of alterations, including a change at the tip of the attack, as Raul Jimenez spearheads the charge after serving his three-match suspension.
Timothy Castagne is also preferred over Kenny Tete on the right-hand side of defence, while Willian returns from a hamstring problem and will line up against his old club alongside two other erstwhile Gunners in Bernd Leno and Alex Iwobi.
Fulham: Leno; Castagne, Bassey, Adarabioyo, Robinson; Palhinha, Cairney; Decordova-Reid, Iwobi, Willian; Jimenez
Subs: Rodak, Tete, Ballo-Toure, Diop, Lukic, Reed, Wilson, Pereira, Muniz
Arsenal: Raya; White, Saliba, Gabriel, Kiwior; Rice, Odegaard, Havertz; Saka, Nketiah, Martinelli
Subs: Ramsdale, Cedric, Tomiyasu, Trossard, Elneny, Smith Rowe, Nelson, Jorginho, Jesus