The Gunners will enter the contest off the back of a thumping 5-0 victory over Chelsea on Tuesday evening, and they are currently top of the table, three points clear of second-placed Liverpool.
Mikel Arteta's side have responded impressively to successive losses against Aston Villa and Bayern Munich, and the capital giants will be eyeing another huge three points this weekend.
Here, Sports Mole rounds up Arsenal's latest injury and suspension news ahead of the clash with Tottenham, who are locked in a battle with Aston Villa for fourth spot in the division.
Jurrien Timber
Status: Major doubt
Type of injury: Knee
Possible return date: April 28 (vs. Tottenham)
Timber made his long-awaited return from an ACL injury for Arsenal Under-21s against Blackburn Rovers Under-21s on Monday night, scoring a stunning goal in the contest. The Netherlands international now has a slight chance of being in the squad for the North London derby on Sunday afternoon.
ARSENAL'S SUSPENSION LIST
Arsenal have no players suspended for this match.
Celta Vigo 
Valencia 
Napoli 
Lecce 
FC Porto 
Sporting CP 
Amorebieta 
Espanyol 
Empoli 
Roma 
Frosinone 
Udinese 
Lazio 
Sassuolo 
Verona 
Inter 
Sevilla 
Barcelona 
Olympiacos Piraeus 
Fiorentina 
AC Milan 
Borussia Dortmund 
Real Madrid 
Atalanta 
Cartagena 
Gibraltar 
Scotland 
Croatia 
North Macedonia 
Albania 
Liechtenstein 
England 
Bosnia & Herzegovina 
Germany 
Ukraine 
Slovenia 
Armenia 
Switzerland 
Estonia 
Romania 
Bulgaria 
Austria 
Serbia 
Portugal 
Finland 
Rep. Of Ireland 
Hungary 
Italy 
Turkey 
San Marino 
Slovakia 
Denmark 
Sweden 
Norway 
Kosovo 
Belgium 
Montenegro