The hosts, who have won just one of their last nine games, have already been relegated from the Turkish Super Lig.
Match preview
Umraniyespor began the month of May with a 4-1 win over Sivasspor, but they were unable to build upon that positive result.
After playing out a 1-1 draw with Istanbul Basaksehir, Mustafa Er's side fell to a 2-1 defeat to Ankaragucu in their most recent outing, confirming their relegation.
Kevin Malcuit opened the scoring before Umut Nayir restored parity from the penalty spot, but Ankaragucu retook the lead through Milson in the 71st minute.
With Umraniyespor unable to find an equaliser, the narrow defeat ensured that their stay in the top flight would last just one season.
Saturday's hosts are only left with pride to play, and they will be looking to claim a league double over Giresunspor after winning January's reverse fixture by a 1-0 scoreline.
Like their hosts, Giresunspor are currently languishing in the relegation zone, but they still have a chance to avoid the drop.
Giresunspor head into Saturday's encounter off the back of a 4-2 defeat against Trabzonspor, which ended a promising three-game unbeaten run.
The result leaves Giresunspor one point adrift from safety, but with 15th-placed Istanbulspor set to be awarded three points for their cancelled game with Gaziantep, there is a possibility that Irfan Buz's side could be relegated this weekend.
Saturday's visitors know that they have to claim all three points if they are to send their relegation fight to the final game of the season.
Having failed to win any of their last nine away league matches, Giresunspor will be looking to claim their first away victory in the Turkish Super Lig since November.
Umraniyespor Turkish Super Lig form:
L
L
L
W
D
L
Giresunspor Turkish Super Lig form:
W
L
L
L
D
L
Team News
Onur Atasayar has missed Umraniyespor's last three matches with an injury issue, and he remains a doubt for Saturday's contest.
Orkun Ozdemir missed the draw against Istanbul Basaksehir through suspension, but the goalkeeper will return to the side this weekend.
After scoring five goals in his last three games, Nayir will be looking to continue his fine form when he leads the line.
As for the visitors, they are unable to call upon Faustin Senghor, while there are doubts over the availability of Alexis Perez.
Vukan Savicevic returned from a spell on the sidelines to feature as a half-time substitute against Trabzonspor, and he could be utilised off the bench once again.
Riad Bajic will feature up front for Giresunspor, and he will be aiming to find the net for a third consecutive game.
Umraniyespor possible starting lineup:
Ozdemir; Popov, Glumac, Epureanu, Eser; Goksu, Sackey, Gheorghe; Ayik, Sekidika, Nayir
Giresunspor possible starting lineup:
Kaplan; Bilazer, Arias, Seven, Uludag; Serginho, Mejia, Campuzano, Saglam, Sainz; Bajic