Les Parisiens will remain without Neymar (ankle) and Presnel Kimpembe (Achilles) for the rest of the season, while Nordi Mukiele and Sergio Ramos may not be back from their calf issues just yet either.
However, Achraf Hakimi was able to turn out for Morocco during the international break, while Carlos Soler and Marquinhos are also in line to return from muscular problems in time for the weekend.
Marquinhos's comeback could tempt Galtier into sticking with a three-man defensive setup, as the Brazilian joins Danilo Pereira and Juan Bernat in front of Gianluigi Donnarumma.
Hakimi will seemingly be given the green light to charge down the right flank, as Nuno Mendes holds his spot on the left with Bernat being utilised as a left-sided centre-half.
With Soler back in the fray, the Spaniard could force compatriot Fabian Ruiz out of the XI to link arms with Vitinha and Marco Verratti in the engine room, although Renato Sanches and Warren Zaire-Emery are also waiting in the wings.
As ever, Kylian Mbappe and Lionel Messi will form their deadly partnership in the final third, as Hugo Ekitike remains confined to minutes from the bench.
Paris Saint-Germain possible starting lineup: Donnarumma; Marquinhos, Pereira, Bernat; Hakimi, Verratti, Vitinha, Soler, Mendes; Messi, Mbappe